By Errol C Friedberg
With a Foreword by means of Sydney Brenner (Nobel laureate in body structure or drugs, 2002)
This biography information the lifetime of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's lifestyles from start, in 1926, to the current, with precise emphasis on his huge, immense clinical contributions, together with being the 1st to advance expertise that resulted in gene cloning technological know-how. In 1980, Berg got a Nobel Prize in chemistry for this work.
as well as his contributions within the examine laboratory, Berg orchestrated and oversaw a old assembly at Asilomar, California that founded on a threatening controversy surrounding the notion by means of a number of the damaging capability of recombinant DNA expertise. This assembly did a lot to stop this controversy and to install position the law of recombinant DNA paintings, therefore placing fears to rest.
The recombinant DNA controversy was once a old consequence of the invention of gene cloning. significantly, it represented a paramount instance of clinical foresight and due diligence by means of the medical neighborhood, instead of by means of regulatory entities within the usa and lots of different nations. the last word attractiveness of gene/DNA cloning resulted in a brand new period of contemporary biology that prospers to the present.
This e-book is aimed basically at scientists and people in education. The e-book strives to easily supply details for the final reader, yet isn't in particular adapted for a basic studying audience.
whereas many books disguise the recombinant DNA controversy, none have satisfactorily addressed this ancient interval and are frequently contradictory concerning the many who is, where's, and why's concerned. also, the good majority of those have been written by way of non-scientists. This biography of Paul Berg presents entry to varied archived letters and files at Stanford collage now not formerly addressed, and to the chronology of occasions as recalled and documented through him, in addition to different key personalities, lots of whom have been interviewed.
Readership: Researchers, graduate scholars, undergraduates in existence sciences, medication and chemistry and lay public.
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Additional info for A Biography of Paul Berg : The Recombinant DNA Controversy Revisited
J Mol Biol 47: 317. 2. Grant proposal to American Cancer Society dated November 26, 1968. Courtesy of Doogab Yi. 3. Berg P. Unpublished essay circa 1968. Personal communication. indd viii 23-05-2014 12:04:10 b1674 The Recombinant DNA Controversy Revisited b1674_Ch-01 CHAPTER ONE Growing up in Brooklyn A pretty rambunctious kid N ew York owns a long history of international immigration. Jewish settlement there dates back to 1654, when a small group of Brazilian Jews fled Portuguese persecution and settled in what was then called New Netherlands.
I once traveled to Japan on a ship during the war and returned with a kimono for Paul’s then current girlfriend, Barbara. But when I presented him with the intended gift he informed me that he and Barbara were no longer an item — and that he had taken up again with Millie! When I was attending law school, a very attractive young woman once approached me and introduced herself as one of Paul’s former girlfriends. She asked after Paul and I told her how well he was doing. That was the expectation of everyone who knew him.
The ships were fitted with one fixed 3-inch cannon and a variety of depth charges for encounters with submarines. They also carried machine guns and anti-aircraft guns. By the end of WWII, the PC owned the proud record of having sunk close to 70 German U-boats. “I don’t think many people appreciated how much American shipping was lost to the German submarines (U-boats) patrolling the Atlantic and wreaking havoc in the Gulf of Mexico,” Berg related. “Britain came very close to losing the war because supplies from the United States were so seriously compromised by German U-boats.
A Biography of Paul Berg : The Recombinant DNA Controversy Revisited by Errol C Friedberg